ABSTRACT
Fibroblasts adhesion on TiAlSiN thin films were examined in vitro. TiAlSiN thin films were deposited on glass coverslips by cathodic arc plasma deposition. The cell adhesion on the TiAlSiN thin films was studied by cell viability, cell proliferation, microtubule cytoskeleton organization and actin cytoskeleton organization and compared with glass and Ti thin film. The cell viability and proliferation rate were significantly higher on the TiAlSiN thin films than on the glass surfaces and Ti films. Fibroblasts on the TiAlSiN thin films had expanded microtubules and well organized actin stress fibers, indicating effective cell adhesion. This study suggests that TiAlSiN coatings might be suitable to support tissue growth on implant surfaces.
keyword : biomaterials, coating, interface, optical, microscopy, fibroblasts
